Jean KRUTMANN, MD

Professor of Dermatology and Environmental Medicine, IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf, GERMANY

Jean Krutmann was born in 1959 in Menden, Germany, and obtained his MD from the University of Münster in 1986. After several stays abroad (postdoc at Case Western Reserve University, Cleveland, Ohio, USA and DFG stipend at the University Hospital for Dermatology in Vienna, Austria) he became resident, assistant/associate professor at the University Hospital for Dermatology of Freiburg. From 1994 until 2001 he was full professor/deputy director of the University Hospital for Dermatology Düsseldorf. In 2001 he was appointed Chair of Environmental Medicine at the Medical Faculty of Heinrich Heine University Düsseldorf and thereby also Director of IUF. Under his directorship in 2011 the institute became a member of the Leibniz Association and was renamed IUF – Leibniz Research Institute for Environmental Medicine.

His research focuses on dermatoxicology, immunodermatology and photodermatology with a special emphasis on environmentally-induced skin diseases and skin aging. He is author/coauthor of more than 400 contributions to scientific journals and books as well as editor of 8 textbooks. Jean Krutmann was awarded several national and international prizes: Arnold Rikli Award, Albrecht Fleckenstein Award, Paul Gerson Unna Award, Oscar Gans Award, CE.R.I.E.S. Research Support Award and the Dermopharmacy Innovation Award. Since 2010, he is member of the Leopoldina, the German National Academy of Science. Since 2012, he is speaker of the Leibniz Research Alliance “Healthy Ageing”. Additionally, he is Distinguished Adjunct Professor at Fudan University in Shanghai, China, since 2017.

 

Top publications

  1. Waldera-Lupa DM, Kalfalah F, Boukamp P, Safferling K, Poschmann G, Gotz-Rosch C; Bernerd F, Haag L, Huebenthal U, Fritsche E, Grabe N, Boege F, Tigges F, Stühler K*, Krutmann J*: Characterization of skin aging associated secreted proteins (SAASP) produced by dermal fibroblasts isolated from intrinsically aged human skin. J Invest Dermatol 135: 1954-1968, 2015. (*Authors contributed equally) IF 6.915
  2. Frauenstein K, Sydlik U, Tigges J, Majora M, Wiek C, Hanenberg H, Abel J, Esser C, Fritsche E, Krutmann J*, Haarmann-Stemmann T*: Evidence for a novel anti-apoptotic pathway in human keratinocytes involving the aryl hydrocarbon receptor, E2F1 and checkpoint kinase 1. Cell Death Differ 20: 1425-1434, 2013. (*Authors contributed equally) IF 8.218
  3. Kamenisch Y*, Fousteri M*, Knoch J, von Thaler AK Fehrenbacher B, Dolle M, Kuiper R, Marc Majora M, Schaller M, van Steeg H, Röcken M, Krutmann J*, Mullenders LH*, Berneburg M: Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging. J Exp Med 207: 379-390, 2010. (*Authors contributed equally) IF 11.240
  4. Fritsche E, Schäfer C, Bernsmann T, Calles C, Wurm M, Hübenthal U, Cline J E, Schroeder P, Rannug A, Klotz L O, Fürst P, Hanenberg H, Abel J, Krutmann J: Lightening up the UV response by identification of the Arylhydrocarbon Receptor as a cytoplasmatic target for ultraviolet B radiation. Proc Natl Acad Sci 104: 8851-8856, 2007. IF 9.423
  5. Schwarz A, Ständer S, Berneburg M, Böhm M, Kulms D, van Steeg H, Große-Heitmeyer K, Krutmann J, Schwarz T: Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair. Nature Cell Biol 4: 26-31, 2002. IF 18.699

 

Talks